595. Characteristics of Antimicrobials Which Affect Parenteral Antibiotic Therapy Outcomes

761A Comparison of Outpatient Parenteral (OP) Antibiotic Therapy (AT) Outcomes: Physician Office and Home Based Therapy

Comparative outcomes of β-lactam antibiotics in outpatient parenteral antibiotic therapy: treatment success, readmissions and antibiotic switches.

OBJECTIVES β-Lactam antibiotics are commonly used in outpatient parenteral antimicrobial therapy (OPAT), but data regarding outcomes of long-term therapy are limited. The purpose of this study was to compare treatment success, readmission and antibiotic switch rates in patients treated with β-lactam antibiotics as OPAT. METHODS We carried out a retrospective review of all patients, discharged...

Patient Characteristics and Outcomes of Outpatient Parenteral Antimicrobial Therapy: A Retrospective Study

Outpatient parenteral antimicrobial therapy (OPAT) is a safe and effective alternative to hospitalization for many patients with infectious diseases. The objective of this study was to describe the OPAT experience at a Canadian tertiary academic centre in the absence of a formal OPAT program. This was achieved through a retrospective chart review of OPAT patients discharged from Sunnybrook Heal...

Ceftriaxone-related agranulocytosis during outpatient parenteral antibiotic therapy.

4 Song W, Moland ES, Hanson ND et al. Failure of cefepime therapy in treatment of Klebsiella pneumoniae bacteremia. J Clin Microbiol 2005; 43: 4891–4. 5 Kim YK, Pai H, Lee HJ et al. Bloodstream infections by extended-spectrum b-lactamase-producing Escherichia coli and Klebsiella pneumoniae in children: epidemiology and clinical outcome. Antimicrob Agents Chemother 2002; 46: 1481–91. 6 Farmer JJ...

Managing an outpatient parenteral antibiotic therapy team: challenges and solutions

Outpatient parenteral antimicrobial therapy (OPAT) programs should strive to deliver safe, cost effective, and high quality care. One of the keys to developing and sustaining a high quality OPAT program is to understand the common challenges or barriers to OPAT delivery. We review the most common challenges to starting and managing an OPAT program and give practical advice on addressing these i...